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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1996-8-15
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pubmed:abstractText |
Bispecific antibodies can be used to redirect cytotoxic T cells to kill virus-infected cells, overriding the need for major histocompatibility complex restriction. We produced a bispecific antibody (3F12) which binds influenza virus M2 protein and the T-cell receptor and can redirect staphylococcal enterotoxin B-activated T cells to kill influenza virus-infected cells and inhibit virus replication in vitro.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1172191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1374685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1476620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1534240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1676265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1824592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1832875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1834746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1899099,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1905015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-1987490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-2521300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-2536060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-2869486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-3108382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-3160953,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-3882238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-6137772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-7536774,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-7608553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-7612225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-7612234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-8168104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8676511-8189055
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bispecific,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Enterotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/M-protein, influenza virus,
http://linkedlifedata.com/resource/pubmed/chemical/M2 protein, Influenza A virus,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/enterotoxin B, staphylococcal
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4800-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8676511-Amino Acid Sequence,
pubmed-meshheading:8676511-Animals,
pubmed-meshheading:8676511-Antibodies, Bispecific,
pubmed-meshheading:8676511-Antibodies, Viral,
pubmed-meshheading:8676511-Cell Line,
pubmed-meshheading:8676511-Dogs,
pubmed-meshheading:8676511-Enterotoxins,
pubmed-meshheading:8676511-Humans,
pubmed-meshheading:8676511-Influenza A virus,
pubmed-meshheading:8676511-Mice,
pubmed-meshheading:8676511-Mice, Inbred BALB C,
pubmed-meshheading:8676511-Molecular Sequence Data,
pubmed-meshheading:8676511-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:8676511-Viral Matrix Proteins,
pubmed-meshheading:8676511-Virus Replication
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pubmed:year |
1996
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pubmed:articleTitle |
A bispecific antibody recognizing influenza A virus M2 protein redirects effector cells to inhibit virus replication in vitro.
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pubmed:affiliation |
Microbiology Department, Mount Sinai Medical Center, New York, New York 10029, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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