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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1996-10-8
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pubmed:abstractText |
The immunosuppressive drug cyclosporin is known to impair renal function. The degree of renal dysfunction is usually estimated from the clearance of creatinine (CCr). Theoretically however, a fall in CCr can be caused by a decrease of GFR, an inhibition of the tubular secretion of creatinine, or the combination of both. CsA has convincingly been shown to decrease GFR, but detailed information on the effects of CsA on tubular secretion of creatinine is lacking.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0931-0509
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
833-6
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8671904-Adult,
pubmed-meshheading:8671904-Cimetidine,
pubmed-meshheading:8671904-Creatinine,
pubmed-meshheading:8671904-Cyclosporine,
pubmed-meshheading:8671904-Female,
pubmed-meshheading:8671904-Glomerular Filtration Rate,
pubmed-meshheading:8671904-Humans,
pubmed-meshheading:8671904-Immunosuppressive Agents,
pubmed-meshheading:8671904-Kidney Transplantation,
pubmed-meshheading:8671904-Kidney Tubules,
pubmed-meshheading:8671904-Male,
pubmed-meshheading:8671904-Middle Aged
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pubmed:year |
1996
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pubmed:articleTitle |
Cyclosporin does not inhibit the tubular secretion of creatinine.
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pubmed:affiliation |
Department of Medicine, Division of Nephrology, University Hospital Nijmegen, P.O. Box 7101, NL-6500 HB Nijmegen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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