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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
Two allergens, BGP-1 and BGP-2, were identified in crude Bermuda grass pollen extract. BGP-1 was a major allergen and elicited a skin reaction in all subjects sensitive to the crude extract, whereas BGP-2 was a minor allergen and elicited a reaction in only 75% of such subjects. Calibrated column chromatography was used to determine the molecular weights and Stokes radii of the allergens. For BGP-1 they were 30 000 daltons and 24,3 X 10(-8) cm respectively and for BGP-2 they were 14 000 daltons and 18,1 X 10(-8) respectively. The sedimentation coefficient (S20,w) of BGP-1 on sucrose density gradient ultracentrifugation was 3,1 and on iso-electric focusing its iso-electric point was found to be pH 5,4. The reason why only certain individuals sensitive to BGP-1 are sensitive to BGP-2 is discussed. It is possible that the former is a dimer of the latter.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0256-9574
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
586-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:867176-Centrifugation, Density Gradient,
pubmed-meshheading:867176-Chromatography, DEAE-Cellulose,
pubmed-meshheading:867176-Humans,
pubmed-meshheading:867176-Isoelectric Point,
pubmed-meshheading:867176-Molecular Weight,
pubmed-meshheading:867176-Plant Extracts,
pubmed-meshheading:867176-Poaceae,
pubmed-meshheading:867176-Pollen,
pubmed-meshheading:867176-Respiratory Hypersensitivity,
pubmed-meshheading:867176-Skin Tests,
pubmed-meshheading:867176-Ultracentrifugation
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pubmed:year |
1977
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pubmed:articleTitle |
Studies on Bermuda grass pollen allergens.
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pubmed:publicationType |
Journal Article
|