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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1996-10-10
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pubmed:abstractText |
We studied 98 in-vitro fertilization (IVF) patients with a high basal follicle stimulating hormone (FSH; >6.5 IU/l) concentration on day 3 who were treated with a low dose gonadotrophin-releasing hormone agonist (GnRHa) protocol and who had received in the previous 6 months a long protocol with GnRHa in a depot formula. The evaluation was made using the previous IVF cycle of the same patient as a control. The mean +/- SD age of the patients was 34.1+/-4.2 years. The use of a low dose agonist protocol ended with significantly less ampoules (37.5 versus 46.1), a shorter duration of stimulation (10.7 versus 12.3 days), a higher oestradiol concentration on day 8 (1068 versus 495 pg/ml), a higher number of mature oocytes (5.9 versus 4.4) and a higher number of good quality embryos (3.3 versus 2.3). The cancellation rate was lower (11 versus 24%). A GnRHa low dose protocol may be the protocol of choice for patients with high FSH concentrations on day 3. Larger randomized studies are needed to confirm these data.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Delayed-Action Preparations,
http://linkedlifedata.com/resource/pubmed/chemical/Follicle Stimulating Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropin-Releasing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Triptorelin Pamoate
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0268-1161
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1169-72
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8671416-Clinical Protocols,
pubmed-meshheading:8671416-Delayed-Action Preparations,
pubmed-meshheading:8671416-Drug Administration Schedule,
pubmed-meshheading:8671416-Female,
pubmed-meshheading:8671416-Fertilization in Vitro,
pubmed-meshheading:8671416-Follicle Stimulating Hormone,
pubmed-meshheading:8671416-Gonadotropin-Releasing Hormone,
pubmed-meshheading:8671416-Humans,
pubmed-meshheading:8671416-Ovulation Induction,
pubmed-meshheading:8671416-Triptorelin Pamoate
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pubmed:year |
1996
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pubmed:articleTitle |
A protocol using a low dose of gonadotrophin-releasing hormone agonist might be the best protocol for patients with high follicle-stimulating hormone concentrations on day 3.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, A Belcere Hospital, 157 Rue de la Porte de Trivaux, 92140 Clamart, France.
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pubmed:publicationType |
Journal Article
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