rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1996-11-27
|
pubmed:abstractText |
The rat olfactory epithelium contains a specific water-soluble 45-kDa protein. This protein is recognized by anti-peptide antibodies which react with alpha-subunits of the known G-proteins. The 45-kDa protein has been isolated using DEAE-chromatography and gel-exclusion chromatography. The content of 45-kDa protein is about 2% of the total soluble proteins of the olfactory mucosa and it is located at the mucociliary surface. According to photo-affinity labeling, the 45-kDa protein possesses a high affinity to GTP and exhibits low GTP hydrolytic activity. The functions of the 45-kDa protein are discussed.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0379-864X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
181-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8670696-Affinity Labels,
pubmed-meshheading:8670696-Amino Acid Sequence,
pubmed-meshheading:8670696-Animals,
pubmed-meshheading:8670696-Antibodies,
pubmed-meshheading:8670696-Epithelium,
pubmed-meshheading:8670696-GTP-Binding Proteins,
pubmed-meshheading:8670696-Guanosine Triphosphate,
pubmed-meshheading:8670696-Immunoblotting,
pubmed-meshheading:8670696-Male,
pubmed-meshheading:8670696-Molecular Sequence Data,
pubmed-meshheading:8670696-Molecular Weight,
pubmed-meshheading:8670696-Olfactory Mucosa,
pubmed-meshheading:8670696-Phosphorus Radioisotopes,
pubmed-meshheading:8670696-Rabbits,
pubmed-meshheading:8670696-Rats,
pubmed-meshheading:8670696-Rats, Wistar,
pubmed-meshheading:8670696-Turbinates
|
pubmed:year |
1996
|
pubmed:articleTitle |
45-kDa GTP-binding protein from rat olfactory epithelium: purification, characterization and localization.
|
pubmed:affiliation |
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|