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pubmed-article:8670291pubmed:abstractText6-Bromoflavone, obtained by bromination of flavanone, binds to central benzodiazepine receptors with a Ki=70 nM and has a clear anxiolytic activity in mice, at 0.5 mg/kg i.p. A survey of the structure/affinity relationship for those receptors in a series of natural and synthetic flavonoids is presented.lld:pubmed
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pubmed-article:8670291pubmed:articleTitle6-Bromoflavone, a high affinity ligand for the central benzodiazepine receptors is a member of a family of active flavonoids.lld:pubmed
pubmed-article:8670291pubmed:affiliationInstituto de Química y Fisicoquímica Biológicas, Facultad de Farmaciay Bioquímica, Buenos Aires, Argentina.lld:pubmed
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