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pubmed-article:8668591pubmed:abstractTextTumor necrosis factor (TNF) is a prototypical inflammatory cytokine with a wide spectrum of biological activities. Therefore it could play a role in many immunologic and non immunologic disorders. We made a review of the literature concerning the significance of high TNF serum levels in pediatrics and also reported our preliminary results on TNF-alpha values in several pediatric immunologic diseases. Our data seem to confirm the importance of TNF in many immunologic disorders and suggest the opportunity of a more extensive analysis of TNF-alpha serum levels in pediatrics.lld:pubmed
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pubmed-article:8668591pubmed:pagination539-43lld:pubmed
pubmed-article:8668591pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:8668591pubmed:articleTitle[Determination of serum levels of tumor necrosis factor in pediatric practice: usefulness and limitations].lld:pubmed
pubmed-article:8668591pubmed:affiliationDivisione di Pediatria, Ospedale Casa Sollievo della Sofferenza, S. Giovanni Rotondo, Italia.lld:pubmed
pubmed-article:8668591pubmed:publicationTypeJournal Articlelld:pubmed
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pubmed-article:8668591pubmed:publicationTypeEnglish Abstractlld:pubmed