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pubmed-article:8666387pubmed:abstractTextA novel human chromosome locus-specific repetitive sequence was identified and characterized using arbitrary PCR. The repeat monomer consensus sequence is 100 bp long, and there are a minimum of 140 to 160 copies of the repetitive sequence per haploid human genome. The repetitive sequence is highly clustered on 20q12 within a 200- to 400-kb region. The highly polymorphic repeat array is inherited in a stable Mendelian fashion. Hybridization analysis revealed detectable conservation of the repeated element only among hominoids and Old World monkeys, where repeat arrangements are also polymorphic.lld:pubmed
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pubmed-article:8666387pubmed:articleTitleHuman genomic characterization of a novel locus-specific repetitive sequence.lld:pubmed
pubmed-article:8666387pubmed:affiliationBIOS Laboratories, Inc., New Haven, Connecticut 06511, USA.lld:pubmed
pubmed-article:8666387pubmed:publicationTypeJournal Articlelld:pubmed
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