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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-8-5
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pubmed:abstractText |
A range of Pseudomonas spp. and other Gram-negative bacteria were screened for induction of antimicrobial activity in response to the autoregulatory factor L-N-(3-oxohexanoyl)homoserine lactone. In one of these, P. aeruginosa ATCC 10145, the production of phenazine metabolites was shown to be inducible in a dose-dependent manner. The production of phenazine-1-carboxamide increased over 50-fold compared to control cultures when supplemented with 200 micrograms/ml of the autoregulator. In addition, the production of an unidentified polar antibacterial substance by this strain increased with autoregulator concentration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0378-1097
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-22
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:8666196-4-Butyrolactone,
pubmed-meshheading:8666196-Bacillus subtilis,
pubmed-meshheading:8666196-Chromatography, High Pressure Liquid,
pubmed-meshheading:8666196-Dose-Response Relationship, Drug,
pubmed-meshheading:8666196-Escherichia coli,
pubmed-meshheading:8666196-Gram-Negative Bacteria,
pubmed-meshheading:8666196-Microbial Sensitivity Tests,
pubmed-meshheading:8666196-Microbiological Techniques,
pubmed-meshheading:8666196-Phenazines,
pubmed-meshheading:8666196-Pheromones,
pubmed-meshheading:8666196-Pseudomonas aeruginosa,
pubmed-meshheading:8666196-Saccharomyces cerevisiae
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pubmed:year |
1996
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pubmed:articleTitle |
Induction of phenazine biosynthesis in cultures of Pseudomonas aeruginosa by L-N-(3-oxohexanoyl)homoserine lactone.
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pubmed:affiliation |
Natural Products Chemistry Section, Glaxo Wellcome Medicines Research Centre, Stevenage, Herts, UK.
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pubmed:publicationType |
Journal Article
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