Linked Life Data

8665161

Source:http://linkedlifedata.com/resource/pubmed/id/8665161

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-8-6
pubmed:abstractText
Xenopus oocyte cytoplasmic poly(A)+ RNA has been shown to include two major complex classes: mRNA and interspersed RNA. The former is defined by its translatability, while the latter consists of non-translatable repeat-containing transcripts with unknown functions. In this study we compared the accumulation patterns of total mRNA and a subfamily of interspersed RNA, the XR family (McGrew & Richter, 1989, Dev. Biol. 134, 267-70). The results showed that the XR interspersed RNA level continued to increase throughout oogenesis, while the total mRNA level reached a peak at late stage II and then decreased as much as 40% between stage II and stage VI of oogenesis. In addition we have found that, like mRNA, only about half of the non-translatable XR interspersed RNA underwent deadenylation at oocyte maturation. This result suggested that about half of the interspersed RNA, like certain mRNAs, also contains the U-rich element to protect it from the automatic deadenylation, implying the poly(A) tail of interspersed RNA may play a role during early development.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0967-1994
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-16
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Differential accumulation of mRNA and interspersed RNA during Xenopus oogenesis and embryogenesis.
pubmed:affiliation
Department of Developmental and Cell Biology, University of California at Irvine, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.