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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1996-10-29
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pubmed:abstractText |
Various observations on the cerebellar vasoreactivity in crossed cerebellar diaschisis (CCD) have previously been reported. The purpose of this study is to clarify the difference between oxygen-15 H2O positron emission tomographic (PET) and technetium-99m hexamethylpropylene amine oxime (HMPAO) single-photon emission tomograph (SPET) findings in CCD and to evaluate the effect of the absolute values of the cerebellar blood flow as measured by 15O-H2O PET on the 99mTc-HMPAO SPET findings. The subjects comprised 15 patients with a supratentorial infarct and CCD. The cerebellar blood flow increased by about 40% at 5 and 20 min after acetazolamide i.v. on both the CCD and the non-CCD side, as measured by 15O-H2O PET. The percentage differences in cerebellar blood flow between the CCD and the non-CCD side were -22.3%+/-5.7% in the resting state, -19. 6%+/-6.4% at 5 min after acetazolamide i.v. and 21.5%+/-6.7% at 20 min after acetazolamide i.v., as measured by 15O-H2O PET, while they were -10.6%+/-5.5% in the resting state and -5.6%+/-5.1% at 5 min after acetazolamide i.v., as measured by 99mTc-HMPAO SPET. After Lassen's linearization correction, the latter two measurements were -16.2%+/-7.7% and -9.6%+/-8.9%, respectively. The effect of acetazolamide did not differ between the CCD and the non-CCD side in 15O-H2O PET, while a greater response on the CCD side was observed in 99mTc-HMPAO SPET, even after Lassen's linearization correction. It is concluded that acetazolamide HMPAO SPET may overestimate the cerebellar vascular response on the CCD side (or underestimate it on the non-CCD side).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetazolamide,
http://linkedlifedata.com/resource/pubmed/chemical/Organotechnetium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Oximes,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium Tc 99m Exametazime,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0340-6997
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
683-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8662103-Acetazolamide,
pubmed-meshheading:8662103-Adult,
pubmed-meshheading:8662103-Aged,
pubmed-meshheading:8662103-Cerebellum,
pubmed-meshheading:8662103-Cerebral Infarction,
pubmed-meshheading:8662103-Cerebrovascular Circulation,
pubmed-meshheading:8662103-Female,
pubmed-meshheading:8662103-Humans,
pubmed-meshheading:8662103-Male,
pubmed-meshheading:8662103-Middle Aged,
pubmed-meshheading:8662103-Organotechnetium Compounds,
pubmed-meshheading:8662103-Oximes,
pubmed-meshheading:8662103-Oxygen Radioisotopes,
pubmed-meshheading:8662103-Technetium Tc 99m Exametazime,
pubmed-meshheading:8662103-Tomography, Emission-Computed,
pubmed-meshheading:8662103-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:8662103-Water
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pubmed:year |
1996
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pubmed:articleTitle |
Cerebellar vascular response to acetazolamide in crossed cerebellar diaschisis: a comparison of 99mTc-HMPAO single-photon emission tomography with 15O-H2O positron emission tomography.
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pubmed:affiliation |
Department of Radiology, Faculty of Medicine, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-82, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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