Linked Life Data

8657408

Source:http://linkedlifedata.com/resource/pubmed/id/8657408

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
1996-7-26
pubmed:abstractText
Deficiency of the 17 beta-hydroxysteroid dehydrogenase (17b-HSD-d) causes female external genital phenotype in spite of 46,XY karyotype and presence of testes due to disorder in biosynthesis of testosterone. However, marked somatic and genital virilization occurs during puberty. Clinical and laboratory investigation of three cases are presented with typical elevation of the precursor steroid androstenedione, and decrease of product steroid testosterone. All the three patients were reared as girls. During puberty orchidectomy was performed in two cases and vaginoplasty in one case. Estrogen replacement therapy contributed to development of female secondary sex characteristics.
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0030-6002
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
137
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
807-10
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[17 beta-hydroxysteroid dehydrogenase defect: female phenotype with 46,XY karyotype].
pubmed:affiliation
Semmelweis Orvostudományi Egyetem, II. sz. Gyermekklinika, Budapest.
pubmed:publicationType
Journal Article, English Abstract, Case Reports