Linked Life Data

8656232

Source:http://linkedlifedata.com/resource/pubmed/id/8656232

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-7-29
pubmed:abstractText
Adjustment of a cognitive test for an expected level of performance improves the discrimination between brain-diseased and healthy subjects. However, this improvement is subject to severe limitations and may be worthwhile only in clinical settings, where test results tend to be low regardless of disease status. The objective of this study was to provide an empirical demonstration of these principles, applied to the detection of dementia with the Mini-Mental State Examination (MMSE). The subjects, derived from a population-based sample, consisted of 36 cases of dementia (23 diagnosed shortly after testing and 13 at follow-up 1 year later) and 301 nondemented subjects defined by a negative follow-up diagnosis. A simulated group of 179 clinically suspect normals was obtained by selecting all cases with an MMSE score below 27. Adjustment was based on the Dutch version (DART) of the National Adult Reading Test (NART), which was highly correlated (0.53) with the MMSE score of nondemented subjects. The results were in accordance with the predictions. We conclude that adjustment is unlikely to improve case finding in representative samples, but can be profitable in clinical practice, where it will be especially helpful in ruling out cerebral disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0895-4356
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
691-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Effects of adjustment on the case-finding potential of cognitive tests.
pubmed:affiliation
Department of Psychiatry of the Free University, Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't