Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-7-29
pubmed:abstractText
This study examined relationships between macronutrients and plasma triglycerides, HDL, and the total-to-HDL cholesterol ratio (T/H ratio) in a population-based sample of 695 premenopausal and 727 postmenopausal women participating in the Framingham Offspring/Spouse Study. Multivariate regression analyses revealed that plasma triglycerides were inversely related to protein, fiber, and polyunsaturated fat and directly related to saturated fat and oleic acid. Alcohol intake was directly related to HDL cholesterol and inversely related to the T/H ratio in all subgroups of women, except for postmenopausal women with the 3/2 or 2/2 apolipoprotein E phenotype. Similarly, a direct relationship between dietary fat and HDL cholesterol was limited to this single subgroup of postmenopausal women. Since dietary fat and alcohol do not appear to have consistent effects on plasma lipids in all groups of women, it is important to consider the genetic contribution to diet/lipid relationships in epidemiological studies and when evaluating lipid-lowering interventions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0895-4356
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
665-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:8656228-Adult, pubmed-meshheading:8656228-Aged, pubmed-meshheading:8656228-Alcohol Drinking, pubmed-meshheading:8656228-Apolipoproteins E, pubmed-meshheading:8656228-Cardiovascular Diseases, pubmed-meshheading:8656228-Cholesterol, pubmed-meshheading:8656228-Cholesterol, HDL, pubmed-meshheading:8656228-Cohort Studies, pubmed-meshheading:8656228-Dietary Fats, pubmed-meshheading:8656228-Female, pubmed-meshheading:8656228-Food Habits, pubmed-meshheading:8656228-Humans, pubmed-meshheading:8656228-Lipoproteins, HDL, pubmed-meshheading:8656228-Massachusetts, pubmed-meshheading:8656228-Menopause, pubmed-meshheading:8656228-Middle Aged, pubmed-meshheading:8656228-Nutrition Surveys, pubmed-meshheading:8656228-Phenotype, pubmed-meshheading:8656228-Risk Factors, pubmed-meshheading:8656228-Triglycerides
pubmed:year
1996
pubmed:articleTitle
Diet and plasma lipids in women. II. Macronutrients and plasma triglycerides, high-density lipoprotein, and the ratio of total to high-density lipoprotein cholesterol in women: the Framingham nutrition studies.
pubmed:affiliation
Ambulatory Nutrition Service, Department of Dietetics, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.