Linked Life Data

8654389

Source:http://linkedlifedata.com/resource/pubmed/id/8654389

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-7-30
pubmed:databankReference
pubmed:abstractText
The sequence of 15.7 kb from the human semenogelin gene locus has been determined. Together with previously published sequences, this gives the structure of a 28-kb region encompassing the two semenogelin genes. The two transcription units are separated by 11616 bp intergenic DNA comprising more than 40% repetitive DNA sequences, predominantly located to a 4-kb block of L1 and Alu repeats. Two more blocks of L1 sequences are present in the DNA flanking the genes, so that approximately 20% of the completed sequence consists of long interspersed repeated sequences, so called LINES. A comparison of the SgI gene and the SgII gene suggests that they evolved by the duplication of an approximately 8 kb DNA segment about 61 million years ago, probably by a mechanism involving recombination between L1 elements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0014-2956
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
235
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
466-70
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
The structure of the semenogelin gene locus--nucleotide sequence of the intergenic and the flanking DNA.
pubmed:affiliation
Department of Clinical Chemistry, Lund University, University Hospital, Malmö, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't