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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1996-7-30
|
| pubmed:abstractText |
In order that there can be confidence that DNA profile frequency estimates will not place undue bias against a defendant, 2 methods are described for estimating minimum allele frequency bounds for PCR-based loci. One approach estimates minimum allele frequencies for VNTR and STR loci using sample size and the observed heterozygosity at a locus, while the second approach, appropriate for loci typed with allele-specific oligonucleotide probes, is based only on sample size. The use of a minimum allele frequency enables compensation for sparse sampling of infrequent alleles in population databases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0937-9827
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
108
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
173-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8652419-DNA Fingerprinting,
pubmed-meshheading:8652419-Gene Frequency,
pubmed-meshheading:8652419-Heterozygote,
pubmed-meshheading:8652419-Humans,
pubmed-meshheading:8652419-Minisatellite Repeats,
pubmed-meshheading:8652419-Models, Genetic,
pubmed-meshheading:8652419-Oligonucleotide Probes,
pubmed-meshheading:8652419-Polymerase Chain Reaction,
pubmed-meshheading:8652419-Sample Size
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Estimating minimum allele frequencies for DNA profile frequency estimates for PCR-based loci.
|
| pubmed:affiliation |
Forensic Science Research and Training Center, FBI Laboratory, FBI Academy, Quantico, Virginia 22135, USA.
|
| pubmed:publicationType |
Journal Article
|