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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1996-7-22
|
| pubmed:abstractText |
Whereas 25 to 50% of selected patients with gynecologic tumors who relapse centrally in an irradiated pelvis can be salvaged by exenteration, postirradiation recurrence infiltrating the pelvic side wall generally has been fatal. We have designed the combined operative and radiotherapeutic treatment (CORT) procedure for the treatment of postirradiation recurrence infiltrating the pelvic wall and developed several new techniques for its realization. The aim of the surgery is as follows: (1) total resection of the tumor with only a microscopic margin (R1) at the pelvic wall, preserving the bony pelvis and the neurovascular support of the leg; (2) modulation of the therapeutic index for a second high-dose irradiation of the pelvic wall by transferring autologous tissue from the abdomen or the thigh, and (3) reconstruction of pelvic organ functions lost due to tumor resection. The tumor bed is irradiated postoperatively with brachytherapy through transcutaneous guide tubes implanted at the pelvic wall.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0008-543X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
77
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1918-33
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8646694-Adult,
pubmed-meshheading:8646694-Age Factors,
pubmed-meshheading:8646694-Aged,
pubmed-meshheading:8646694-Brachytherapy,
pubmed-meshheading:8646694-Combined Modality Therapy,
pubmed-meshheading:8646694-Disease Progression,
pubmed-meshheading:8646694-Disease-Free Survival,
pubmed-meshheading:8646694-Feasibility Studies,
pubmed-meshheading:8646694-Female,
pubmed-meshheading:8646694-Follow-Up Studies,
pubmed-meshheading:8646694-Genital Neoplasms, Female,
pubmed-meshheading:8646694-Humans,
pubmed-meshheading:8646694-Middle Aged,
pubmed-meshheading:8646694-Neoplasm Invasiveness,
pubmed-meshheading:8646694-Neoplasm Recurrence, Local,
pubmed-meshheading:8646694-Pelvic Exenteration,
pubmed-meshheading:8646694-Pelvic Neoplasms,
pubmed-meshheading:8646694-Postoperative Complications,
pubmed-meshheading:8646694-Prospective Studies,
pubmed-meshheading:8646694-Quality of Life,
pubmed-meshheading:8646694-Radiotherapy Dosage,
pubmed-meshheading:8646694-Surgical Flaps,
pubmed-meshheading:8646694-Survival Rate,
pubmed-meshheading:8646694-Transplantation, Autologous
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Five-year experience with combined operative and radiotherapeutic treatment of recurrent gynecologic tumors infiltrating the pelvic wall.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Mainz Medical School, Germany.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|