rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
|
pubmed:dateCreated |
1996-7-22
|
pubmed:abstractText |
More than 50% of breast ductal carcinomas in situ (DCIS) contain significant histologic necrosis, an important prognostic factor for determining recurrence and progression to invasive breast cancer. We have examined whether the mechanism of this spontaneous cell death might be apoptosis, a genetically encoded suicide pathway that may be triggered by various events including dysregulated cell proliferation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0008-543X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
77
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1831-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8646681-Apoptosis,
pubmed-meshheading:8646681-Breast Neoplasms,
pubmed-meshheading:8646681-Carcinoma, Ductal, Breast,
pubmed-meshheading:8646681-Carcinoma in Situ,
pubmed-meshheading:8646681-Cell Death,
pubmed-meshheading:8646681-Cell Division,
pubmed-meshheading:8646681-Cell Nucleus,
pubmed-meshheading:8646681-Coloring Agents,
pubmed-meshheading:8646681-DNA Damage,
pubmed-meshheading:8646681-DNA Nucleotidylexotransferase,
pubmed-meshheading:8646681-Deoxyuracil Nucleotides,
pubmed-meshheading:8646681-Disease Progression,
pubmed-meshheading:8646681-Female,
pubmed-meshheading:8646681-Genes, p53,
pubmed-meshheading:8646681-Humans,
pubmed-meshheading:8646681-Immunohistochemistry,
pubmed-meshheading:8646681-Mutation,
pubmed-meshheading:8646681-Necrosis,
pubmed-meshheading:8646681-Neoplasm Invasiveness,
pubmed-meshheading:8646681-Neoplasm Recurrence, Local,
pubmed-meshheading:8646681-Prognosis
|
pubmed:year |
1996
|
pubmed:articleTitle |
Extensive apoptosis in ductal carcinoma in situ of the breast.
|
pubmed:affiliation |
Division of Pediatric Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|