Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1996-7-12
pubmed:abstractText
Previously, we characterized a rat cDNA for testis-specific transcription elongation factor S-II (SII-T1) (Q. Xu et al., J. Biol. Chem. 269, 3100-3103 (1994)). Here, we isolated a 335-bp fragment of the cDNA for mouse SII-T1, and used it to examine the expression of the SII-T1 gene in the testis by in situ hybridization. The results indicated that the SII-T1 gene is expressed exclusively in spermatocytes, showing no appreciable expression in spermatogonia, spermatids, or Leydig cells. RT-PCR experiments using testis RNA from W/Wv mutant mice also suggested that SII-T1 is a specific transcription elongation factor essential for spermatogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
385
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8641458-Amino Acid Sequence, pubmed-meshheading:8641458-Animals, pubmed-meshheading:8641458-Base Sequence, pubmed-meshheading:8641458-Cloning, Molecular, pubmed-meshheading:8641458-DNA, pubmed-meshheading:8641458-DNA, Complementary, pubmed-meshheading:8641458-Gene Expression Regulation, pubmed-meshheading:8641458-In Situ Hybridization, pubmed-meshheading:8641458-Male, pubmed-meshheading:8641458-Mice, pubmed-meshheading:8641458-Mice, Mutant Strains, pubmed-meshheading:8641458-Molecular Sequence Data, pubmed-meshheading:8641458-Organ Specificity, pubmed-meshheading:8641458-RNA, Messenger, pubmed-meshheading:8641458-Sequence Homology, Amino Acid, pubmed-meshheading:8641458-Spermatocytes, pubmed-meshheading:8641458-Testis, pubmed-meshheading:8641458-Transcription Factors, pubmed-meshheading:8641458-Transcription Factors, General, pubmed-meshheading:8641458-Transcriptional Elongation Factors
pubmed:year
1996
pubmed:articleTitle
Spermatocyte-specific expression of the gene for mouse testis-specific transcription elongation factor S-II.
pubmed:affiliation
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
pubmed:publicationType
Journal Article