| pubmed-article:8641369 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0368761 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0249989 | lld:lifeskim |
| pubmed-article:8641369 | lifeskim:mentions | umls-concept:C0439677 | lld:lifeskim |
| pubmed-article:8641369 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8641369 | pubmed:dateCreated | 1996-7-17 | lld:pubmed |
| pubmed-article:8641369 | pubmed:abstractText | A ligand for the flt3 tyrosine kinase receptor (flt3R) has recently been cloned. Forty-three cases of childhood acute myeloid leukemia (AML) and 27 cases of childhood acute lymphocytic leukemia (ALL) were examined by flow cytometric analysis for cell-surface flt3R and proliferative response in vitro to flt3 ligand (flt3L). Flt3R was commonly expressed on the cell surface of leukemic cells from all AML subclasses and B-ALL, but we did not detect cell-surface flt3R on T-ALL. Flt3L alone induced the proliferation of the monocytic AML-M5 cells and some erythroleukemic AML-M6 cells. Some isolated instances of weak proliferative responses were also noted in other AML subclasses. Interleukin-4 (IL-4) alone inhibited the proliferation of a group of AML-M5 cells and, when combined with flt3L, suppressed the proliferative effect of flt3L. In general, B-ALL and T-ALL cells failed to respond to flt3L alone or in the presence of combinations of IL-2, IL-3, or IL-7. | lld:pubmed |
| pubmed-article:8641369 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8641369 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8641369 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8641369 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8641369 | pubmed:issn | 0301-472X | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:BernsteinI... | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:WilliamsD EDE | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:SmithF OFO | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:McKennaH JHJ | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:LymanS DSD | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:BraselKK | lld:pubmed |
| pubmed-article:8641369 | pubmed:author | pubmed-author:HirschsteinDD | lld:pubmed |
| pubmed-article:8641369 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8641369 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:8641369 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8641369 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8641369 | pubmed:pagination | 378-85 | lld:pubmed |
| pubmed-article:8641369 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:8641369 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8641369 | pubmed:articleTitle | Effects of flt3 ligand on acute myeloid and lymphocytic leukemic blast cells from children. | lld:pubmed |
| pubmed-article:8641369 | pubmed:affiliation | Immunex Research and Development Corp., Seattle, WA 98101, USA. | lld:pubmed |
| pubmed-article:8641369 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8641369 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8641369 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8641369 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8641369 | lld:pubmed |
