rdf:type |
|
lifeskim:mentions |
umls-concept:C0003018,
umls-concept:C0010453,
umls-concept:C0019134,
umls-concept:C0019143,
umls-concept:C0020564,
umls-concept:C0021289,
umls-concept:C0028778,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035820,
umls-concept:C0205102,
umls-concept:C0225828,
umls-concept:C0567416,
umls-concept:C0851285
|
pubmed:issue |
4
|
pubmed:dateCreated |
1996-7-15
|
pubmed:abstractText |
Heparan sulfate, one of the primary components of extracellular matrix, is a potent antigrowth factor in certain types of cells. To elucidate a possible role of endogenous heparin-like molecules in regulating cardiomyocyte hypertrophy, we investigated the effects of heparin and heparan sulfate on angiotensin (Ang) II-induced hypertrophy in cultured neonatal rat cardiomyocytes.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0009-7322
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
93
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
810-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8641011-Angiotensin II,
pubmed-meshheading:8641011-Animals,
pubmed-meshheading:8641011-Cardiomegaly,
pubmed-meshheading:8641011-Cells, Cultured,
pubmed-meshheading:8641011-Heart,
pubmed-meshheading:8641011-Heparin,
pubmed-meshheading:8641011-Heparin Lyase,
pubmed-meshheading:8641011-Heparitin Sulfate,
pubmed-meshheading:8641011-Humans,
pubmed-meshheading:8641011-Hypertrophy,
pubmed-meshheading:8641011-Leucine,
pubmed-meshheading:8641011-Myocardium,
pubmed-meshheading:8641011-Polysaccharide-Lyases,
pubmed-meshheading:8641011-Rats,
pubmed-meshheading:8641011-Recombinant Proteins
|
pubmed:year |
1996
|
pubmed:articleTitle |
Heparin and heparan sulfate block angiotensin II-induced hypertrophy in cultured neonatal rat cardiomyocytes. A possible role of intrinsic heparin-like molecules in regulation of cardiomyocyte hypertrophy.
|
pubmed:affiliation |
Second Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|