rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1996-7-3
|
pubmed:abstractText |
This study was designed to determine the relation of valproate serum levels to clinical improvement and development of adverse effects in hospitalized patients with acute mania. The initial fixed-dose escalation design, the monotherapy with divalproex, and the control of variables that is possible only with hospitalized patients reduced the confounding factors present in most outpatient studies of serum level-response relationships.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0002-953X
|
pubmed:author |
pubmed-author:BowdenC LCL,
pubmed-author:CalabreseJ RJR,
pubmed-author:DavisJ MJM,
pubmed-author:GoodnickPP,
pubmed-author:JanicakP GPG,
pubmed-author:KimmelS ESE,
pubmed-author:MorrisD DDD,
pubmed-author:OrsulakPP,
pubmed-author:RischS CSC,
pubmed-author:RushA JAJ,
pubmed-author:SmallJ GJG,
pubmed-author:SwannA CAC
|
pubmed:issnType |
Print
|
pubmed:volume |
153
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
765-70
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8633687-Acute Disease,
pubmed-meshheading:8633687-Adult,
pubmed-meshheading:8633687-Bipolar Disorder,
pubmed-meshheading:8633687-Dose-Response Relationship, Drug,
pubmed-meshheading:8633687-Double-Blind Method,
pubmed-meshheading:8633687-Drug Administration Schedule,
pubmed-meshheading:8633687-Female,
pubmed-meshheading:8633687-Hospitalization,
pubmed-meshheading:8633687-Humans,
pubmed-meshheading:8633687-Male,
pubmed-meshheading:8633687-Placebos,
pubmed-meshheading:8633687-Psychiatric Status Rating Scales,
pubmed-meshheading:8633687-Treatment Outcome,
pubmed-meshheading:8633687-Valproic Acid
|
pubmed:year |
1996
|
pubmed:articleTitle |
Relation of serum valproate concentration to response in mania.
|
pubmed:affiliation |
Department of Psychiatry, University of Texas Health Science Center, San Antonio 78284-7792, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|