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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1996-7-2
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pubmed:abstractText |
The objective of this study was to investigate the in vivo relationship between plasma free fatty acid (FFA)/albumin molar ratio and indicators of cellular damage. A case series study was carried out in 20 geriatric patients in a stable clinical condition. Their plasma albumin concentration was in the range 26-42 g l-1. There was a significant positive correlation between the FFA/albumin ratio and (a) reticulocyte count (r = 0.61, p = 0.006), (b) lactate dehydrogenase activity (r = 0.69, p = 0.002), and (c) haptoglobin concentration (r = 0.46, p = 0.05). The haemoglobin concentration was inversely related to relative reticulocyte count (r = -0.55, p = 0.01). Absolute and relative reticulocyte counts were positively associated (r = 0.92, p < 0.0001). The results are in accordance with the contention that a high FFA/albumin ratio in vivo may elicit cellular damage. Further studies are required to elucidate to what extent a high FFA/albumin ratio might be causally related to diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0036-5513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
649-53
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8633190-Aged,
pubmed-meshheading:8633190-Aged, 80 and over,
pubmed-meshheading:8633190-Cells,
pubmed-meshheading:8633190-Fatty Acids, Nonesterified,
pubmed-meshheading:8633190-Female,
pubmed-meshheading:8633190-Hemoglobins,
pubmed-meshheading:8633190-Humans,
pubmed-meshheading:8633190-L-Lactate Dehydrogenase,
pubmed-meshheading:8633190-Male,
pubmed-meshheading:8633190-Regression Analysis,
pubmed-meshheading:8633190-Reticulocyte Count,
pubmed-meshheading:8633190-Serum Albumin
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pubmed:year |
1995
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pubmed:articleTitle |
Blood reticulocyte count and plasma lactate dehydrogenase activity are positively related to the free fatty acid/albumin ratio in geriatric patients.
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pubmed:affiliation |
Department of Preventive Medicine, University of Oslo, Norway.
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pubmed:publicationType |
Journal Article
|