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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1977-7-18
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pubmed:abstractText |
In a patient a papilla Vateri tumor completely prevented the bile-pancreatic flow into the intestine although the pancreatic juice was secreted into the bile duct via a common channel. Consequently, the bile-pancreatic juice was possible to sample via a percutaneous transhepatic cholangiography (PTC) catheter. This made it possible to study the effect of duodenal infusion of different substances on the bile-pancreatic secretion. In repeated experiments a suppression of the secretion was observed by intraduodenal trypsin as well as the patient's own bile-pancreatic juice. In the presence the bile-pancreatic juice intraduodenal trypsin inhibitor infusion caused a marked stimulation of the secretion. The results are in accordance with the hypothesis that trypsin in the upper part of the intestine exerts a negative feedback regulation of the pancreatic secretion in man.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0012-2823
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
303-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:863133-Aged,
pubmed-meshheading:863133-Amylases,
pubmed-meshheading:863133-Bile Ducts,
pubmed-meshheading:863133-Duodenal Neoplasms,
pubmed-meshheading:863133-Feedback,
pubmed-meshheading:863133-Humans,
pubmed-meshheading:863133-Lipase,
pubmed-meshheading:863133-Male,
pubmed-meshheading:863133-Pancreas,
pubmed-meshheading:863133-Pancreatic Juice,
pubmed-meshheading:863133-Secretory Rate,
pubmed-meshheading:863133-Time Factors,
pubmed-meshheading:863133-Trypsin,
pubmed-meshheading:863133-Trypsin Inhibitors
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pubmed:year |
1977
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pubmed:articleTitle |
Feedback regulation of pancreatic enzyme secretion by intestinal trypsin in man.
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pubmed:publicationType |
Journal Article,
Case Reports
|