Linked Life Data

863093

Source:http://linkedlifedata.com/resource/pubmed/id/863093

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Suppl
pubmed:dateCreated
1977-7-18
pubmed:abstractText
The usefulness of measuring plasma concentrations of drugs in patients is now well established and permits a greater efficacy and safety of treatment since dosage can be adjusted on an individual basis. In monitoring plasma concentrations one must recognize that a number of factors may influence these levels. For instance, levels may be affected by age, body-weight and size, genetical factors, abnormalities of water and electrolyte balance and complications associated with pathological conditions such as renal and hepatic impairment. Likewise, plasma levels will depend on dosage, time and route of drug administration, the bioavailability of the drug and time of blood sampling. In addition, absorption, distribution, metabolism, excretion and concurrent drug administration may profoundly affect plasma drug concentrations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-0605
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
82-97
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Factors influencing plasma drug concentrations.
pubmed:publicationType
Journal Article