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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
The retinoic acid derivative Ro 10-9359, given orally in maximum daily doses of 100 mg to 15 patients with psoriasis vulgaris, led to clearing of the lesions in 8 patients. The average period of treatment was 9 weeks. In 14 patients side-effects were observed, the most important being palmo-plantar desquamation, shivering, thirst and diffuse hair loss. In 2 patients scaling led to withdrawal. In 6 patients abnormal alkaline phosphatase and glutamic-aspartatic transaminase values, partly transient, developed (glutamicaspartatic transaminase, p less than 0.01).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0011-9075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
154
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:863067-Alkaline Phosphatase,
pubmed-meshheading:863067-Aspartate Aminotransferases,
pubmed-meshheading:863067-Drug Evaluation,
pubmed-meshheading:863067-Female,
pubmed-meshheading:863067-Humans,
pubmed-meshheading:863067-Male,
pubmed-meshheading:863067-Psoriasis,
pubmed-meshheading:863067-Time Factors,
pubmed-meshheading:863067-Tretinoin,
pubmed-meshheading:863067-Vitamin A
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pubmed:year |
1977
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pubmed:articleTitle |
Treatment of psoriasis vulgaris with a new retinoic acid derivative Ro 10-9359; An uncontrolled clinical trial.
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pubmed:publicationType |
Journal Article
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