| pubmed-article:8628662 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8628662 | lifeskim:mentions | umls-concept:C0229304 | lld:lifeskim |
| pubmed-article:8628662 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:8628662 | lifeskim:mentions | umls-concept:C0037633 | lld:lifeskim |
| pubmed-article:8628662 | lifeskim:mentions | umls-concept:C1382100 | lld:lifeskim |
| pubmed-article:8628662 | lifeskim:mentions | umls-concept:C0896246 | lld:lifeskim |
| pubmed-article:8628662 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8628662 | pubmed:dateCreated | 1996-6-26 | lld:pubmed |
| pubmed-article:8628662 | pubmed:abstractText | The solution conformations of the dinucleotide d(TT) and the modified duplex d(CGCGAATTCGCG)2 with N3'--> P5' phosphoramidate internucleoside linkages have been studied using circular dichroism (CD) and NMR spectroscopy. The CD spectra indicate that the duplex conformation is similar to that of isosequential phosphodiester RNA, a A-type helix, and is different from that of DNA, a B-type helix, NMR studies of model dimers d(TpT) and N3'--> P5' phosphoramidate d(TnpT) show that the sugar ring conformation changes from predominantly C2'-endo to C3'-endo when the 3'-phosphoester is replaced by a phosphoramidate group. Two-dimensional NMR (NOESY, DQF-COSY and TOCSY spectra) studies of the duplex provide additional details about the A-type duplex conformation of the oligonucleotide phosphoramidate and confirm that all furanose rings of 3'-aminonucleotides adopt predominantly N-type sugar puckering. | lld:pubmed |
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| pubmed-article:8628662 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8628662 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8628662 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8628662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:8628662 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8628662 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8628662 | pubmed:issn | 0305-1048 | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:WilsonW DWD | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:LloydD HDH | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:YaoSS | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:PanYY | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:DingDD | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:Chandrasekara... | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:RatmeyerLL | lld:pubmed |
| pubmed-article:8628662 | pubmed:author | pubmed-author:GrayaznovS... | lld:pubmed |
| pubmed-article:8628662 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8628662 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:8628662 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:8628662 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8628662 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8628662 | pubmed:pagination | 354-60 | lld:pubmed |
| pubmed-article:8628662 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:8628662 | pubmed:meshHeading | pubmed-meshheading:8628662-... | lld:pubmed |
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| pubmed-article:8628662 | pubmed:meshHeading | pubmed-meshheading:8628662-... | lld:pubmed |
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| pubmed-article:8628662 | pubmed:meshHeading | pubmed-meshheading:8628662-... | lld:pubmed |
| pubmed-article:8628662 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8628662 | pubmed:articleTitle | An oligodeoxyribonucleotide N3'--> P5' phosphoramidate duplex forms an A-type helix in solution. | lld:pubmed |
| pubmed-article:8628662 | pubmed:affiliation | Department of Chemistry, Georgia State University, Atlanta, 30303, USA. | lld:pubmed |
| pubmed-article:8628662 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8628662 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8628662 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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