| pubmed-article:8627069 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8627069 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:8627069 | lifeskim:mentions | umls-concept:C0085508 | lld:lifeskim |
| pubmed-article:8627069 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:8627069 | lifeskim:mentions | umls-concept:C0010868 | lld:lifeskim |
| pubmed-article:8627069 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8627069 | pubmed:dateCreated | 1996-6-21 | lld:pubmed |
| pubmed-article:8627069 | pubmed:abstractText | The interrelationship between cytotoxin-associated gene A (CagA), vacuolating cytotoxin (VacA), and Helicobacter pylori-related diseases was investigated in 155 H. pylori-infected patients. Four (7%) of 60 subjects had mixed cagA+ and cagA- H. pylori infections. The H. pylori isolates from 98.3% of 121 patients with anti-CagA antibodies were cagA+. The occurrence of cagA+ H. pylori among 76 patients with peptic ulcer disease (PUD) was higher (93.4%) than among 79 patients with functional dyspepsia (FD; 64.6%) (odds ratio [OR] = 7.80; P < .001). VacA+ isolates were isolated from 56.6% of the PUD patients and 35.4% of the FD patients (OR = 2.37; P = .0132). For type I (cagA+VacA+) isolates, these numbers were 56.6% and 31.6%, respectively (P = .003). Only 4% of the 71 VacA+ isolates were cagA-. In addition, 37% of the patients with PUD were infected with cagA+VacA- H. pylori. Chi 2 results did not improve when VacA was entered into the model in the presence of cagA, indicating that only cagA is associated with PUD. | lld:pubmed |
| pubmed-article:8627069 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8627069 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8627069 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8627069 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8627069 | pubmed:month | May | lld:pubmed |
| pubmed-article:8627069 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:DankertJJ | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:TytgatG NGN | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:FellerMM | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:WeelJ FJF | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:GerritsYY | lld:pubmed |
| pubmed-article:8627069 | pubmed:author | pubmed-author:RoordaPP | lld:pubmed |
| pubmed-article:8627069 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8627069 | pubmed:volume | 173 | lld:pubmed |
| pubmed-article:8627069 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8627069 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8627069 | pubmed:pagination | 1171-5 | lld:pubmed |
| pubmed-article:8627069 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8627069 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8627069 | pubmed:articleTitle | The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related diseases. | lld:pubmed |
| pubmed-article:8627069 | pubmed:affiliation | University of Amsterdam, Department of Medical Microbiology, Netherlands. | lld:pubmed |
| pubmed-article:8627069 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8627069 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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