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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1996-6-21
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pubmed:abstractText |
From previous experiments it is known that the murine dominant cataract mutants carrying the gene Cat2 have a decreased content of gamma-crystallin-specific transcripts in the juvenile lens, when the cataract is completely expressed. Moreover, the mutant locus has been mapped recently to chromosome 1, closely linked to the gamma E-crystallin gene (map distance 0.3 +/- 0.3 cM). In the present paper we describe the phenotypic changes and the gamma-crystallin expression in embryonic lenses of the Cat2nop mutants as an example for the Cat2 allelic series.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0721-832X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
233
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
795-800
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8626090-Alleles,
pubmed-meshheading:8626090-Animals,
pubmed-meshheading:8626090-Cataract,
pubmed-meshheading:8626090-Crystallins,
pubmed-meshheading:8626090-Embryonic and Fetal Development,
pubmed-meshheading:8626090-In Situ Hybridization,
pubmed-meshheading:8626090-Lens, Crystalline,
pubmed-meshheading:8626090-Mice,
pubmed-meshheading:8626090-Mice, Mutant Strains,
pubmed-meshheading:8626090-Mutation,
pubmed-meshheading:8626090-Phenotype,
pubmed-meshheading:8626090-RNA, Messenger,
pubmed-meshheading:8626090-RNA Probes,
pubmed-meshheading:8626090-Transcription, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
Reduced levels of gamma-crystallin transcripts during embryonic development of murine Cat2nop mutant lenses.
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pubmed:affiliation |
Post-Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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