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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-6-21
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pubmed:abstractText |
We have developed a 14C-urea breath test to follow the course of Helicobacter felis infection in mice. Peak 14CO2 production occurred approximately 8 min after substrate administration. The test values were compared to those from a rapid urease test and correlated with the presence of pathogens by histology. The sensitivity was 99%, specificity 91%, positive predictive value 95% and negative predictive value 99% when the assay was conducted in fasted mice. We conclude that in mice the breath test analysis is a useful noninvasive method for detecting the presence of H. felis or for evaluating therapeutic agents affecting growth or survival of the organism.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0012-2823
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
30-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8626045-Animals,
pubmed-meshheading:8626045-Breath Tests,
pubmed-meshheading:8626045-Carbon Radioisotopes,
pubmed-meshheading:8626045-Female,
pubmed-meshheading:8626045-Helicobacter,
pubmed-meshheading:8626045-Helicobacter Infections,
pubmed-meshheading:8626045-Mice,
pubmed-meshheading:8626045-Mice, Inbred BALB C,
pubmed-meshheading:8626045-Sensitivity and Specificity,
pubmed-meshheading:8626045-Stomach,
pubmed-meshheading:8626045-Urea
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pubmed:year |
1996
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pubmed:articleTitle |
Carbon-14-urea breath test as a noninvasive method to monitor Helicobacter felis colonization in mice.
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pubmed:affiliation |
Department of Gastroenterology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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