| pubmed-article:8626020 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0680022 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0013935 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1446409 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C0036488 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1704735 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:8626020 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:8626020 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8626020 | pubmed:dateCreated | 1996-6-25 | lld:pubmed |
| pubmed-article:8626020 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:abstractText | In this paper we present a structural and functional characterization of a new sea urchin embryo transcription factor, SpRunt-1. This factor was isolated by means of its specific interaction with a cis-regulatory target site of the CyIIIa gene. Here we show that this target site, the P7I site, is required for normal embryonic activation of CyIIIa x CAT reporter gene constructs. An oligonucleotide affinity column bearing the P7I target site purifies a 21-kDa polypeptide from blastula-stage nuclear extracts, and the amino acid sequence obtained from this polypeptide was used to generate a nucleic acid probe with which the corresponding cDNA was cloned. The cDNA encodes an approximately 60-kDa protein, SpRunt-1, which includes a "runt domain" that is closely homologous to those of Drosophila and mammalian runt domain transcription factors. RNA and genomic blots show that SpRunt-1 is represented by a single embryonic transcript, encoded by one of possibly two runt-domain-containing genes. By RNA probe protection we found that transcripts of SpRunt-1 increase in concentration dramatically after the blastula stage of development, suggesting that the up-regulation of CyIIIa that occurs after blastula stage is a function of zygotically transcribed SpRunt-1. These results are discussed with reference to known features of the runt domain family of transcription factors. | lld:pubmed |
| pubmed-article:8626020 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8626020 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8626020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8626020 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8626020 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8626020 | pubmed:issn | 0012-1606 | lld:pubmed |
| pubmed-article:8626020 | pubmed:author | pubmed-author:HarringtonM... | lld:pubmed |
| pubmed-article:8626020 | pubmed:author | pubmed-author:DavidsonE HEH | lld:pubmed |
| pubmed-article:8626020 | pubmed:author | pubmed-author:CoffmanJ AJA | lld:pubmed |
| pubmed-article:8626020 | pubmed:author | pubmed-author:KirchhamerC... | lld:pubmed |
| pubmed-article:8626020 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8626020 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:8626020 | pubmed:volume | 174 | lld:pubmed |
| pubmed-article:8626020 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8626020 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8626020 | pubmed:pagination | 43-54 | lld:pubmed |
| pubmed-article:8626020 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:meshHeading | pubmed-meshheading:8626020-... | lld:pubmed |
| pubmed-article:8626020 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8626020 | pubmed:articleTitle | SpRunt-1, a new member of the runt domain family of transcription factors, is a positive regulator of the aboral ectoderm-specific CyIIIA gene in sea urchin embryos. | lld:pubmed |
| pubmed-article:8626020 | pubmed:affiliation | Division of Biology 156-29, California Institute of Technology, Pasadena, California 91125, USA. | lld:pubmed |
| pubmed-article:8626020 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8626020 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8626020 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:8626020 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:373468 | entrezgene:pubmed | pubmed-article:8626020 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8626020 | lld:pubmed |
