Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1996-6-21
|
| pubmed:abstractText |
Alveolar rhabdomyosarcoma is an aggressive childhood tumor that exhibits muscle cell differentiation. Cytogenetically, it is characterized by t(2;13)(q35;q14); no consistent secondary abnormalities have been reported. Cytogenetic analysis of bone marrow in a case of alveolar rhabdomyosarcoma revealed t(2;13)(q35;q14) and der(16)t(1;16)(q21;q13). The present case and a review of the literature suggest that up to 11% of these tumors possess der(16)t(1;16)(q21;q13). This is similar to the incidence observed in the Ewing family of tumors, where unbalanced der(16)t(1;16) translocations, resulting in partial trisomy of 1q, are regarded as a consistent secondary cytogenetic change.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0165-4608
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
87
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
179-81
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8625268-Child,
pubmed-meshheading:8625268-Chromosomes, Human, Pair 1,
pubmed-meshheading:8625268-Chromosomes, Human, Pair 16,
pubmed-meshheading:8625268-Humans,
pubmed-meshheading:8625268-Karyotyping,
pubmed-meshheading:8625268-Male,
pubmed-meshheading:8625268-Rhabdomyosarcoma, Alveolar,
pubmed-meshheading:8625268-Soft Tissue Neoplasms,
pubmed-meshheading:8625268-Translocation, Genetic
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
der(16)t(1;16)(q21;q13) as a secondary change in alveolar rhabdomyosarcoma. A case report and review of the literature.
|
| pubmed:affiliation |
Section of Pediatrics, Institute of Cancer Research, Sutton, Surrey, U.K.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|