Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-6-27
pubmed:abstractText
This review focuses on two topics that in the past decade have significantly enhanced our understanding of the mechanisms by which bacteria produce disease in humans: population structures of bacterial pathogens and tactics used by these bacteria to gain entry to mammalian cells. Studies in these areas have identified a number of virulence factors of some medically important pathogens. Very recent applications of this knowledge in efforts to understand mechanisms by which the most extensively studied "putative" periodontal pathogens, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, may contribute to the pathogenesis of periodontitis are presented. Knowledge of the population structures of these periodontopathic bacterial species and the mechanisms used by these bacteria to subvert host cell communication systems and functions will shape future approaches to diagnosis, prevention, and treatment of periodontal diseases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:issn
1065-626X
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
New insights into mechanisms of bacterial pathogenesis in periodontitis.
pubmed:affiliation
Indiana University School of Dentistry, Indianapolis, USA.
pubmed:publicationType
Journal Article, Review