8622064

Source:http://linkedlifedata.com/resource/pubmed/id/8622064

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008059, umls-concept:C0034897, umls-concept:C0085669, umls-concept:C0146224, umls-concept:C0205373, umls-concept:C0332157, umls-concept:C0444889
pubmed:issue	5
pubmed:dateCreated	1996-6-18
pubmed:abstractText	To determine the maximum-tolerated systemic exposure (MTSE) and exposure-limiting toxicity of continuous infusion topotecan in children with recurrent acute leukemia.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P01-CA20180, http://linkedlifedata.com/resource/pubmed/grant/P30-CA21765
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8309333
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin, http://linkedlifedata.com/resource/pubmed/chemical/Topotecan
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0732-183X
pubmed:author	pubmed-author:BakerS DSD, pubmed-author:EvansW EWE, pubmed-author:FurmanW LWL, pubmed-author:PrattC BCB, pubmed-author:RiveraG KGK, pubmed-author:StewartC FCF
pubmed:issnType	Print
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1504-11
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:8622064-Acute Disease, pubmed-meshheading:8622064-Adolescent, pubmed-meshheading:8622064-Adult, pubmed-meshheading:8622064-Antineoplastic Agents, pubmed-meshheading:8622064-Camptothecin, pubmed-meshheading:8622064-Child, pubmed-meshheading:8622064-Child, Preschool, pubmed-meshheading:8622064-Dose-Response Relationship, Drug, pubmed-meshheading:8622064-Female, pubmed-meshheading:8622064-Half-Life, pubmed-meshheading:8622064-Humans, pubmed-meshheading:8622064-Infant, pubmed-meshheading:8622064-Infusions, Intravenous, pubmed-meshheading:8622064-Leukemia, pubmed-meshheading:8622064-Male, pubmed-meshheading:8622064-Metabolic Clearance Rate, pubmed-meshheading:8622064-Recurrence, pubmed-meshheading:8622064-Topotecan
pubmed:year	1996
pubmed:articleTitle	Escalating systemic exposure of continuous infusion topotecan in children with recurrent acute leukemia.
pubmed:affiliation	Department of Hematology-Oncology, St Jude Children's Research Hospital, Memphis, TN 38105, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase I