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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1996-6-6
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pubmed:abstractText |
The Santa Lucia strain of Plasmodium falciparum and the Aotus lemurinus griseimembra monkey are proposed as models for the testing of sporozoite vaccines and transmission-blocking vaccines. Approximately 85% of splenectomized monkeys were infected when fed upon by 10 or more heavily infected Anopheles freeborni mosquitoes. Sporozoite-induced infections in monkeys with or without previous infection with P. vivax readily infected mosquitoes, thus making them candidates for testing transmission-blocking vaccines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-9637
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
372-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8615450-Animals,
pubmed-meshheading:8615450-Anopheles,
pubmed-meshheading:8615450-Aotus trivirgatus,
pubmed-meshheading:8615450-Child, Preschool,
pubmed-meshheading:8615450-Disease Models, Animal,
pubmed-meshheading:8615450-El Salvador,
pubmed-meshheading:8615450-Female,
pubmed-meshheading:8615450-Humans,
pubmed-meshheading:8615450-Insect Vectors,
pubmed-meshheading:8615450-Malaria, Falciparum,
pubmed-meshheading:8615450-Malaria Vaccines,
pubmed-meshheading:8615450-Parasitemia,
pubmed-meshheading:8615450-Plasmodium falciparum,
pubmed-meshheading:8615450-Splenectomy
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pubmed:year |
1996
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pubmed:articleTitle |
The Santa Lucia strain of Plasmodium falciparum as a model for vaccine studies. I. Development in Aotus lemurinus griseimembra monkeys.
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pubmed:affiliation |
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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