Linked Life Data

8615303

Source:http://linkedlifedata.com/resource/pubmed/id/8615303

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-6-5
pubmed:abstractText
The pathogenesis of mitral regurgitation (MR) was determined by quantitative echocardiography in 188 patients with acute myocardial infarction (AMI) within 48 hours after admission. MR was classified, by using color Doppler, as significant (grades 3 to 4) or trivial (grades 0 to 2). Left ventricular (LV) function (global and regional), volume, and shape, as well as mitral valvular features, were measured and analyzed by stepwise logistic regression. Significant MR occurred in 25 (13%) patients. Univariately, recurrent infarction (p < 0.01), LV dilation (p < 0.001) and sphericity (p < 0.001), inferoposterolateral asynergy (p < 0.001), mitral annular dilatation (p < 0.005), and mitral leaflet restriction (p < 0.05) were associated with significant MR. In regression analysis, only recurrent infarction (odds ratio 5.08), LV sphericity index (odds ratio 1.12), and inferoposterolateral asynergy (odds ratio 6.07) were independently associated with significant MR, whereas none of the mitral valvular features examined had an independent association. In conclusion, changes in LV shape and regional function and not mitral valvular changes are prime determinants of significant MR after AMI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
131
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
865-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Pathogenesis of mitral regurgitation in acute myocardial infarction: importance of changes in left ventricular shape and regional function.
pubmed:affiliation
Academic Medical Center, Department of Cardiology, Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't