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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1996-6-6
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pubmed:abstractText |
Mice deficient in either alpha beta or gamma delta T cells were more susceptible to infection with the protozoan parasite Cryptosporidium parvum than were control mice. Both neonatal and adult alpha beta-T-cell-deficient mice developed chronic infection. Gamma delta-T-cell-deficient neonatal mice were more susceptible than control mice but were able to clear the infection. Adult gamma delta-T-cell-deficient mice were not susceptible to infection. These data indicate that alpha beta T cells are important for resistance to C. parvum while gamma delta T cells have a less critical role.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1359428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1500156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1604321,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1677668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1695022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1717333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-1828619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-2108092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-2384671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-2660260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-3343052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-6607888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7589086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7597094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7905464,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7905921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7946037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-7973709,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8081650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8103040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8216921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8278391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8361537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8381716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8613403-8478105
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1854-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8613403-Animals,
pubmed-meshheading:8613403-Animals, Newborn,
pubmed-meshheading:8613403-CD4-Positive T-Lymphocytes,
pubmed-meshheading:8613403-Chronic Disease,
pubmed-meshheading:8613403-Cryptosporidiosis,
pubmed-meshheading:8613403-Cryptosporidium parvum,
pubmed-meshheading:8613403-Female,
pubmed-meshheading:8613403-Male,
pubmed-meshheading:8613403-Mice,
pubmed-meshheading:8613403-Mice, Inbred C57BL,
pubmed-meshheading:8613403-Mice, Mutant Strains,
pubmed-meshheading:8613403-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:8613403-Receptors, Antigen, T-Cell, gamma-delta
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pubmed:year |
1996
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pubmed:articleTitle |
Cryptosporidium parvum infection in T-cell receptor (TCR)-alpha- and TCR-delta-deficient mice.
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pubmed:affiliation |
Metabolic Diseases and Immunology Research Unit, National Animal Disease Center, US Department of Agriculture, Ames, Iowa 50010-0070, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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