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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-6-5
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pubmed:abstractText |
Most antidepressant and neuroleptic agents are metabolized by the polymorphic cytochrome P450 enzyme CYP2D6. This study evaluates the importance of the CYP2D6 genotype for the disposition of the neuroleptic agents perphenazine and zuclopenthixol.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0009-9236
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
423-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8612387-Administration, Oral,
pubmed-meshheading:8612387-Adolescent,
pubmed-meshheading:8612387-Adult,
pubmed-meshheading:8612387-Aged,
pubmed-meshheading:8612387-Aged, 80 and over,
pubmed-meshheading:8612387-Antipsychotic Agents,
pubmed-meshheading:8612387-Bayes Theorem,
pubmed-meshheading:8612387-Clopenthixol,
pubmed-meshheading:8612387-Cytochrome P-450 CYP2D6,
pubmed-meshheading:8612387-Cytochrome P-450 Enzyme System,
pubmed-meshheading:8612387-Genotype,
pubmed-meshheading:8612387-Humans,
pubmed-meshheading:8612387-Middle Aged,
pubmed-meshheading:8612387-Mixed Function Oxygenases,
pubmed-meshheading:8612387-Perphenazine,
pubmed-meshheading:8612387-Prospective Studies
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pubmed:year |
1996
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pubmed:articleTitle |
The CYP2D6 genotype predicts the oral clearance of the neuroleptic agents perphenazine and zuclopenthixol.
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pubmed:affiliation |
Department of Clinical Pharmacology, Karolinska Institute, Huddinge Hospital, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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