Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1996-5-30
|
pubmed:abstractText |
Associations of carotid artery diameter and intimal-medial thickness by ultrasound with echocardiographic left ventricular (LV) structure were examined in 3,409 participants in the Cardiovascular Health Study, a population-based study of risk factors for coronary heart disease and stroke in men and women aged > or = 65 years. At baseline, sector-guided M-mode echocardiography and B-mode ultrasound were used to evaluate the left ventricle and carotid arteries, respectively. Common carotid artery diameter and intimal-medial thickness were significantly related to LV mass in correlational analysis (r=0.40 and 0.20, respectively, p<0.01), and each was independently associated with LV mass after adjustment for age, gender, weight, systolic and diastolic blood pressure, antihypertensive medication use, prior coronary heart disease, electrocardiographic abnormalities, high-density lipoprotein, and factor VII. We speculate that changes in the arterial wall affect impedance to LV ejection leading to increases in LV mass. Further follow-up of this cohort is in progress and will help to determine whether such carotid artery measures could, by exacerbating LV hypertrophy, constitute another important risk factor for adverse cardiovascular outcomes.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0002-9149
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
77
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
628-33
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:8610615-Aged,
pubmed-meshheading:8610615-Carotid Arteries,
pubmed-meshheading:8610615-Cohort Studies,
pubmed-meshheading:8610615-Female,
pubmed-meshheading:8610615-Heart Ventricles,
pubmed-meshheading:8610615-Humans,
pubmed-meshheading:8610615-Hypertrophy, Left Ventricular,
pubmed-meshheading:8610615-Male,
pubmed-meshheading:8610615-Regression Analysis,
pubmed-meshheading:8610615-Risk Factors
|
pubmed:year |
1996
|
pubmed:articleTitle |
Carotid artery measures are strongly associated with left ventricular mass in older adults (a report from the Cardiovascular Health Study).
|
pubmed:affiliation |
Department of Biostatistics, University of Washington, Seattle, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|