|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1996-5-28
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|
pubmed:abstractText |
Electrochemotherapy (ECT) is a new antitumor approach that combines systemic bleomycin (BLM) with electric pulses (EP) delivered locally at the tumor site. These EP permeabilize the cells in the tissue, allow BLM delivery inside the cells, and increase BLM cytotoxicity. As an extension of our initial Phase I trial on patients with head and neck squamous cell carcinoma (HNSCC) permeation nodules, we tested variations of ECT protocol to determine how to improve it.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0008-543X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
77
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
956-63
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:8608490-Adult,
pubmed-meshheading:8608490-Aged,
pubmed-meshheading:8608490-Antibiotics, Antineoplastic,
pubmed-meshheading:8608490-Bleomycin,
pubmed-meshheading:8608490-Breast Neoplasms,
pubmed-meshheading:8608490-Cell Membrane Permeability,
pubmed-meshheading:8608490-Combined Modality Therapy,
pubmed-meshheading:8608490-Electrodes,
pubmed-meshheading:8608490-Electrophysiology,
pubmed-meshheading:8608490-Female,
pubmed-meshheading:8608490-Head and Neck Neoplasms,
pubmed-meshheading:8608490-Humans,
pubmed-meshheading:8608490-Injections, Intravenous,
pubmed-meshheading:8608490-Male,
pubmed-meshheading:8608490-Middle Aged,
pubmed-meshheading:8608490-Neoplasm Recurrence, Local,
pubmed-meshheading:8608490-Transcutaneous Electric Nerve Stimulation
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|
pubmed:year |
1996
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|
pubmed:articleTitle |
Antitumor electrochemotherapy: new advances in the clinical protocol.
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|
pubmed:affiliation |
Department of Head and Neck Oncology, Institut Gustave-Roussy, Villejuif, France.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
|
