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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-5-29
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pubmed:abstractText |
Effects of the dopamine-related drug bromocriptine (BCT) on event-related potentials (ERP) were investigated in 18 healthy volunteers. Bromocriptine 2.5 mg or an inactive placebo was administered according to a completely randomized double-blind, cross-over design. The ERP were recorded 3 h after medication was given. Although BCT prolonged the P300 latency, it had no effect on the amplitudes of the ERP components as a whole. Bromocriptine increased the latencies of N100, P200 and P300 in the respective short-latency subject group, and decreased the latency of N200 in the long-latency subject group. It increased the amplitude of N200 in the low-amplitude subject group. It was concluded that the prolongation of P300 latency as a whole and the different responses that take place are dependent on the initial values and were recognized in the effect of a single administration of BCT 2.5 mg. The results of this study are discussed in relation to the law of initial value.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1323-1316
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-86
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8608441-Adolescent,
pubmed-meshheading:8608441-Adult,
pubmed-meshheading:8608441-Bromocriptine,
pubmed-meshheading:8608441-Cross-Over Studies,
pubmed-meshheading:8608441-Dose-Response Relationship, Drug,
pubmed-meshheading:8608441-Double-Blind Method,
pubmed-meshheading:8608441-Ergot Alkaloids,
pubmed-meshheading:8608441-Evoked Potentials,
pubmed-meshheading:8608441-Evoked Potentials, Auditory,
pubmed-meshheading:8608441-Humans,
pubmed-meshheading:8608441-Male,
pubmed-meshheading:8608441-Placebos
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pubmed:year |
1995
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pubmed:articleTitle |
Effects of the dopamine-related drug bromocriptine on event-related potentials and its relation to the law of initial value.
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pubmed:affiliation |
Department of Neuropsychiatry, School of Medicine, University of the Ryukyus, Okinawa, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|