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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1996-5-17
|
| pubmed:abstractText |
The objective of this study was to evaluate the effect of fetal blood sampling on cardiac flow velocity waveforms. Flow velocity waveforms were measured from the ascending aorta and pulmonary artery immediately before and after fetal blood sampling in 29 normally grown and 12 growth-retarded fetuses. The latter group was characterized by abnormal Doppler indices in the umbilical artery and middle cerebral artery suggestive of uteroplacental insufficiency as the causative factor of the impaired growth. The flow velocity parameters studied were the peak velocity, the time to peak velocity, and the left and right cardiac output and their ratio. In normally grown fetuses, the peak velocity and right and left cardiac output values increased significantly after fetal blood sampling, while no significant changes were observed in the other indices considered. The gestational age at the time of the procedure was positively related to the amplitude of these changes. In growth-retarded fetuses, fetal blood sampling did not induce any significant increase in cardiac output or peak velocities, while in more than 50 per cent of the fetuses these Doppler indices decreased. The amplitude of the decrease was significantly related to the severity of acidosis in the umbilical vein. In conclusion, the cardiac haemodynamic response to fetal blood sampling differs between normally grown and growth-retarded fetuses. This difference may explain the higher rate of complications occurring in the latter group of fetuses after blood sampling.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0197-3851
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1007-16
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8606879-Blood Flow Velocity,
pubmed-meshheading:8606879-Blood Specimen Collection,
pubmed-meshheading:8606879-Cardiac Output,
pubmed-meshheading:8606879-Coronary Circulation,
pubmed-meshheading:8606879-Female,
pubmed-meshheading:8606879-Fetal Blood,
pubmed-meshheading:8606879-Fetal Growth Retardation,
pubmed-meshheading:8606879-Fetus,
pubmed-meshheading:8606879-Gestational Age,
pubmed-meshheading:8606879-Humans,
pubmed-meshheading:8606879-Pregnancy
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Cardiac flow after fetal blood sampling in normally grown and growth-retarded fetuses.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, Università di Roma, Tor Vergata, Italy.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|