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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-5-23
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pubmed:databankReference |
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pubmed:abstractText |
The sequence of the enteroaggregative Escherichia coli enterotoxin 1 ( EAST1) gene was present in most (or all) strains of human-colonizing enterotoxigenic E. coli (ETEC) with colonization factor antigen II (CFA/II) or CFA/IV (CS6). The EAST1 gene was also strongly associated with PCF09+ ETEC or CFA/I+ ETEC elaborating heat-liable enterotoxin (and heat-stable enterotoxin I). In contrast, CFA/I+ ETEC elaborating heat-stable enterotoxin I, CFA/III+ ETEC, or CS17+ ETEC exhibited very weak or no associated. E. coli from healthy volunteers had no EAST1 gene sequence. A CFA/I+ ETEC strain (H10407) possessed multiple copies of the EAST1 gene on the CFA/I-encoding plasmid and chromosome. In one CFA/II+ ETEC strain, the EAST1 gene was present on the CFA/II-encoding plasmid. The EAST1 gene sequences of the CFA/I+ and CFA/II+ ETEC strains were identical to each other and 99.1% homologous to the reported gene sequence of enteroaggregative E. coli. The data indicate that the EAST1 gene is distributed among ETEC strains with a case of the presence of multiple copies in a single cell and that this distribution is associated with the adherence factor type.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1100526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-13267987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1480112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1658721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1671111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1774313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1828771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-1969831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2010554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2189007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2572553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2656875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2671906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-2827159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-3313248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-336541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-3402544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-3510984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-3543152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-3934291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-4553083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-6146568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-6298182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-6352687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-7009583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-7433111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-80383,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-8126624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-8385356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8606115-8463396
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1441-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1996
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pubmed:articleTitle |
Detection of the enteroaggregative Escherichia coli heat-stable enterotoxin 1 gene sequences in enterotoxigenic E. coli strains pathogenic for humans.
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pubmed:affiliation |
Department of Infectious Diseases and Tropical Medicine, Research Institute, International Medical Center of Japan, Tokyo.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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