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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1996-5-3
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pubmed:abstractText |
The published sequence of the herpes simplex virus (HSV) type 2 strain HG52 neurovirulence gene RL1 indicated that, unlike the HSV-1 homologue, the gene contains a 154 bp intron. This intron contains six complete and one partial copy of a 19 bp repeat which encodes a stop codon; thus all three forward frames are blocked. By RT-PCR of poly(A)+ RNA, using primers on either side of the proposed intron, we have isolated a partial cDNA clone corresponding to the predicted spliced mRNA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
77 ( Pt 3)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
481-4
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pubmed:dateRevised |
2006-9-22
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pubmed:meshHeading |
pubmed-meshheading:8601785-Base Sequence,
pubmed-meshheading:8601785-DNA, Viral,
pubmed-meshheading:8601785-Exons,
pubmed-meshheading:8601785-Genes, Viral,
pubmed-meshheading:8601785-Herpesvirus 2, Human,
pubmed-meshheading:8601785-Introns,
pubmed-meshheading:8601785-Viral Proteins,
pubmed-meshheading:8601785-Virulence
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pubmed:year |
1996
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pubmed:articleTitle |
The herpes simplex virus type 2 strain HG52 RL1 gene contains a 154 bp intron as predicted from sequence analysis.
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pubmed:affiliation |
MRC Virology Unit, Institute of Virology, Glasgow, UK.
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pubmed:publicationType |
Journal Article
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