Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-5-9
pubmed:abstractText
The carbon dioxide (CO2) laser can be used for rapid, detailed sculpting of cartilage for creation of an ear framework for reconstruction of microtia. Clinical and animal studies of the effect of the CO2 laser have noted good healing with little evidence of a zone of tissue injury adjacent to the laser incisions. The current study has investigated the longer term effect of CO2 on chondrocyte viability in a rabbit ear model in which the laser has been used to incise autogenous cartilage segments for implantation into subcutaneous pockets. Over a 3-month period, the conformational integrity of the segments, when compared to segments incised with a scalpel, was no different. However, radioactive sulfur uptake studies to assess the viability of chondrocytes indicated a decrease in chondrocyte density in those specimens that have been subjected to laser incisions. Although other studies of acute cellular injury indicate that the CO2 laser may be beneficial for cartilage incision and sculpting, the current study indicates that resorption over longer periods of time might be encountered as a consequence of decreased chondrocyte viability in the vicinity of the laser incisions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1049-2275
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-50
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effect of the carbon dioxide laser on viability of ear cartilage in a rabbit model.
pubmed:affiliation
Department of Surgery, University of Tennessee, Memphis, USA.
pubmed:publicationType
Journal Article, Comparative Study