Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1996-5-2
pubmed:abstractText
The importance of surface topology and implant material composition on osseointegration in trabecular bone was investigated using three commericially used implant materials and surface-texturing procedures which included blasting, high temperature acid etching, and hydroxyapatite (HA) coating. Surface roughness and spacing parameters were measured for each implant group with a laser interferometric profilometer. Cylindrical implants were press-fit into trabecular bone sites in the knee of mature miniature pigs. After 12 weeks in situ, osseointegration was evaluated by (1) mechanical pushout tests to measure bone-implant interface strength and (2) quantitative morphometric measurements of the percent implant surface covered by bone. We found that HA-coated implants showed superior osseointegration in terms of both pushout failure load and surface coverage by bone measurements. An excellent correlation (r2 = .90) was found between the average roughness of the implant surface and pushout failure load. New methods for altering the local topologic and/or chemical state of the implant surface (i.e., by acid etching) may provide an important new avenue of research for improving the osseointegrative properties of orthopedic materials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-9304
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1567-75
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effect of surface topology on the osseointegration of implant materials in trabecular bone.
pubmed:affiliation
M. E. Müller Institute for Biomechanics, University of Bern, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't