| pubmed-article:8597950 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0027361 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0036864 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0039215 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0332157 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C1836231 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0439064 | lld:lifeskim |
| pubmed-article:8597950 | lifeskim:mentions | umls-concept:C0205345 | lld:lifeskim |
| pubmed-article:8597950 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8597950 | pubmed:dateCreated | 1996-4-22 | lld:pubmed |
| pubmed-article:8597950 | pubmed:abstractText | Some individuals remain uninfected with human immunodeficiency virus type-1 (HIV-1) despite multiple high-risk sexual exposures. We studied a cohort of 25 subjects with histories of multiple high-risk sexual exposures to HIV-1 and found that their CD8+ lymphocytes had greater anti-HIV-1 activity than did CD8+ lymphocytes from nonexposed controls. Further studies indicated that their purified CD4+ lymphocytes were less susceptible to infection with multiple primary isolates of HIV-1 than were CD4+ lymphocytes from the nonexposed controls. This relative resistance to HIV-1 infection did not extend to T-cell line-adapted strains, was restricted by the envelope glycoprotein, was not explained by the cell surface density of CD4 molecules, but was associated with the activity of the C-C chemokines RANTES, MIP-1alpha, and MIP-1beta. This relative resistance of CD4+ lymphocytes may contribute to protection from HIV-1 in multiply exposed persons. | lld:pubmed |
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| pubmed-article:8597950 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8597950 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8597950 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8597950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8597950 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8597950 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8597950 | pubmed:issn | 1078-8956 | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:MartinS RSR | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:KotlerD PDP | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:TsuTT | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:WolinskyS MSM | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:O'BrienT RTR | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:PadianNN | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:BraunJ FJF | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:KoupR ARA | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:SkurnickJJ | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:PaxtonW AWA | lld:pubmed |
| pubmed-article:8597950 | pubmed:author | pubmed-author:VanDevanterN... | lld:pubmed |
| pubmed-article:8597950 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8597950 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:8597950 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8597950 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8597950 | pubmed:pagination | 412-7 | lld:pubmed |
| pubmed-article:8597950 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8597950 | pubmed:meshHeading | pubmed-meshheading:8597950-... | lld:pubmed |
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| pubmed-article:8597950 | pubmed:meshHeading | pubmed-meshheading:8597950-... | lld:pubmed |
| pubmed-article:8597950 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8597950 | pubmed:articleTitle | Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. | lld:pubmed |
| pubmed-article:8597950 | pubmed:affiliation | Aaron Diamond AIDS Research Center, New York, New York 10016, USA. | lld:pubmed |
| pubmed-article:8597950 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8597950 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8597950 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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