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| pubmed-article:8596038 | lifeskim:mentions | umls-concept:C1521970 | lld:lifeskim |
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| pubmed-article:8596038 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:8596038 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8596038 | pubmed:dateCreated | 1996-4-15 | lld:pubmed |
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| pubmed-article:8596038 | pubmed:abstractText | The TCR V beta element is pivotal for superantigen recognition; however, not all T cells bearing a particular V beta element respond to an individual superantigen. Recent evidence has indicated that the TCR V alpha element also contributes to recognition of superantigen/MHC class II complexes. To determine whether the TCR beta-chain junctional regions influence recognition of a superantigen encoded by mouse mammary tumor virus (MMTV) proviral integrant Mtv-1, we have analyzed these regions in T cells that have survived superantigen-mediated negative selection in B10.BR-Mtv-1 mice. Our data indicate: 1) no TCR J beta skewing, 2) no difference in the length of the third complementarity-determining region (CDR3), and 3) no outstanding structural features that are shared among the junctional regions of the V beta 3+ T cells that escape thymic clonal elimination in superantigen-expressing mice. Several possible models for TCR engagement of viral superantigen/MHC class II complexes are discussed. | lld:pubmed |
| pubmed-article:8596038 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8596038 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8596038 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8596038 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8596038 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8596038 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8596038 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:8596038 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:8596038 | pubmed:author | pubmed-author:PullenA MAM | lld:pubmed |
| pubmed-article:8596038 | pubmed:author | pubmed-author:BogatzkiL YLY | lld:pubmed |
| pubmed-article:8596038 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8596038 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:8596038 | pubmed:volume | 156 | lld:pubmed |
| pubmed-article:8596038 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8596038 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8596038 | pubmed:pagination | 1865-72 | lld:pubmed |
| pubmed-article:8596038 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:meshHeading | pubmed-meshheading:8596038-... | lld:pubmed |
| pubmed-article:8596038 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8596038 | pubmed:articleTitle | Receptors on T cells escaping superantigen-mediated deletion lack special beta-chain junctional region structural characteristics. | lld:pubmed |
| pubmed-article:8596038 | pubmed:affiliation | Department of Immunology, University of Washington, Seattle, WA 98195, USA. | lld:pubmed |
| pubmed-article:8596038 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8596038 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8596038 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8596038 | lld:pubmed |
