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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1996-4-9
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pubmed:databankReference |
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pubmed:abstractText |
Large terminal fragments of human chromosomes 2p, 6p, 8q, 12q, and 18q were cloned using yeast artificial chromosomes (YACs). RecA-assisted restriction endonuclease (RARE) cleavage analysis of genomic DNA samples from II unrelated individuals using YAC-derived probes confirmed the telomeric localizations of the half-YACs studied. The cloned fragments provide telomeric closure of maps for the respective chromosome arms and will supply the reagents needed for analyzing and sequencing these distal subtelomeric regions.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1088-9051
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8593610-Base Sequence,
pubmed-meshheading:8593610-Chromosomes, Artificial, Yeast,
pubmed-meshheading:8593610-Chromosomes, Human,
pubmed-meshheading:8593610-Chromosomes, Human, Pair 12,
pubmed-meshheading:8593610-Chromosomes, Human, Pair 18,
pubmed-meshheading:8593610-Chromosomes, Human, Pair 2,
pubmed-meshheading:8593610-Chromosomes, Human, Pair 6,
pubmed-meshheading:8593610-Chromosomes, Human, Pair 8,
pubmed-meshheading:8593610-Cloning, Molecular,
pubmed-meshheading:8593610-Humans,
pubmed-meshheading:8593610-In Situ Hybridization, Fluorescence,
pubmed-meshheading:8593610-Molecular Sequence Data,
pubmed-meshheading:8593610-Polymerase Chain Reaction,
pubmed-meshheading:8593610-Restriction Mapping,
pubmed-meshheading:8593610-Telomere
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pubmed:year |
1995
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pubmed:articleTitle |
Molecular cloning and RARE cleavage mapping of human 2p, 6q, 8q, 12q, and 18q telomeres.
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pubmed:affiliation |
Wistar Institute, Philadelphia, Pennsylvania 19104, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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