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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1996-4-11
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pubmed:abstractText |
The callosal projection is traditionally believed to be exclusively excitatory in function. A new method combining lectin-conjugated colloidal gold for retrograde tracing with immunofluorescence for GABA was used to investigate this question. The large majority of neurons retrogradely labeled after injections of tracer into contralateral S-I were GABA-negative cells in layers II-VI. However, GABA-positive neurons projecting to contralateral S-I were also seen. The majority of double-labeled cells were only weakly labeled with tracer; they were located both in superficial and deep cortical layers and represented at least 1% of all retrogradely labeled neurons. Neurons double-labeled for both tracer and GABA in upper layers were found mainly within the central patch of callosally projecting neurons, whereas those in deep layers were scattered throughout contralateral cortex.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholera Toxin,
http://linkedlifedata.com/resource/pubmed/chemical/Gold Colloid,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/gamma-Aminobutyric Acid
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
697
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-34
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8593589-Animals,
pubmed-meshheading:8593589-Cerebral Cortex,
pubmed-meshheading:8593589-Cholera Toxin,
pubmed-meshheading:8593589-Corpus Callosum,
pubmed-meshheading:8593589-Gold Colloid,
pubmed-meshheading:8593589-Immunohistochemistry,
pubmed-meshheading:8593589-Lectins,
pubmed-meshheading:8593589-Male,
pubmed-meshheading:8593589-Neural Pathways,
pubmed-meshheading:8593589-Neurons,
pubmed-meshheading:8593589-Peptide Fragments,
pubmed-meshheading:8593589-Rats,
pubmed-meshheading:8593589-Rats, Sprague-Dawley,
pubmed-meshheading:8593589-gamma-Aminobutyric Acid
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pubmed:year |
1995
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pubmed:articleTitle |
GABA-immunopositive neurons in rat neocortex with contralateral projections to S-I.
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pubmed:affiliation |
Department of Cell Biology and Anatomy, University of North Carolina, Chapel Hill 27599, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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